Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. 5) Vein Diseases and Swelling. Help your body fight the effects of normal aging. Blood pressure is an important measure of how much blood is pumping from your heart to the rest of your body. (9), Related:Top 7 Benefits of Green Tea: The No. Your email address will not be published. While OPCs found in this extract are mostly known for their antioxidant-producing benefits, these amazing compounds exude antibacterial, antiviral, anticarcinogenic, anti-aging, anti-inflammatory and anti-allergic properties. Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. Another one of its exemplary effects is helping manage blood pressure levels. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. Score one for diabetes control and fewer risk factors for the heart. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. - Please read carefully and implement principles included in the Health Recovery Plan. All rights reserved. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. 3. All of our content is written by scientists and people with a strong science background. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Can you get pycnogenol naturally from foods? New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. There were 88 in the control group and 81 in the Pycnogenol group. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. painful urination. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. It may cause side effects such as: Risks. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Vertigo. There's good evidence that pycnogenol helps with eye damage caused by diabetes. Pycnogenol has four main components that contribute to its benefits for men's health. Today's Dietitian: "Pycnogenol Supplement Offers Promise for Managing a Variety of Conditions." Regardless of what youre using it for, its best to start with the lowest possible dose. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. (2015). It also slightly decreased blood pressure and increased testosterone [67]. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. Pycnogenol in metabolic syndrome and related disorders [Abstract]. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. Pycnogenol acts as a sustained-release formulation. The study participants symptoms started to return a month after they stopped taking pine bark extract. 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Are there any risks to taking it? 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Pycnogenol lowered leukotrienes as well. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Eye health. Studies on human subjects have reported few side effects - even . Headaches. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. Helps Increase Athletic Performance. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. Some research suggests that procyanidins may have antioxidant and anti-inflammatory activity. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. What gives pine bark extract its notoriety as a powerful ingredient and super antioxidant is that its loaded with oligomeric proanthocyanidin compounds, OPCs for short. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. Flavonoids and proanthocyanidins within these fruits can . First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . During the first month on L-arginine, only five percent of patients experienced normal erection. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. is a clickable link to peer-reviewed scientific studies. Natural Factors Pycnogenol 100mg 30 Veggie Caps. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. Learn more about how to get even skin tone. For asthma in children: 1 milligram per pound of body weight given in two divided doses. All rights reserved. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. Moreover, Pycnogenol treatment reduced the use of painkillers. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. Early research shows that taking it at least 5 weeks before the start of allergy season seems to lessen symptoms. You should also avoid using pine bark extract without talking to your doctor first if you: You should also do additional research or talk to your doctor before taking pine bark extract if you also take: While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. A Pycnogenol combination product (with l-arginine, alpha lipoic acid, B vitamins, and vitamin K2) may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [39]. The extract has been widely studied for the past 40 . Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. DIM and other plant indoles are found in . However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. from the bark of the French maritime pine tree. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. There are several causes for erectile dysfunction, such as neurological and psychological issues. There havent been enough studies yet to change practice protocols for treating children. (2017). If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. Instead, use plain water to wipe yourself and then dry your bottom afterward. View as: Grid List. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. Healthline Media does not provide medical advice, diagnosis, or treatment. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. Pycnogenol also treatment improved blood vessel function. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Pycnogenol is the registered trademark brand name of French maritime pine bark extract. 2. Additionally, athletes have endured less cramping and muscle pain when using the extract. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. Disclaimer: Results are not guaranteed*** and may vary from person to person***. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Pine bark extract is usually taken by mouth in capsule form. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. The authors attributed the negative results to the short duration of treatment and the low dosages of drug or Pycnogenol. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. Set Ascending Direction. Organika Pycnogenol 50mg 100 Tablets. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Prunes and prune juice have many health benefits. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. Pycnogenol (pic-noj-en-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits. Eliminate blood clots. Pycnogenol and Pine Bark Extract Supplements. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. They were given Pycnogenolfor a period of 10 days. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. $109.99. In this article, well summarize all the potential benefits and the scientific research surrounding pine bark extract and Pycnogenol. Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. SelfDecode does not treat, diagnose or cure any conditions, It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. However, in all the above studies insulin levels did not change. Quality and active ingredients in supplements may vary widely from maker to maker. A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. Pycnogenol significantly improved the heavy feeling as well as the swelling. DOI: Dvorkov M, et al. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. It had the best results when combined with compression stockings, but worked just as well alone [28]. Pycnogenol seems well-tolerated for use in adults for up to 6 months. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Joe Cohen flipped the script on conventional and alternative medicine and it worked. (4). This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. That way, your doctor can check on any potential side effects or interactions with medications. $31.99. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. He learned about the seemingly omnipotent antioxidant within it and how those antioxidants increase the absorption of vitamin C. Continued research showed that the pine bark contained flavonols and bioflavonoids, which hold tissue-repairing properties. But what are its health benefits? Remember to speak with a doctor before taking Pycnogenol. Inhibits platelet aggregation like low-dose aspirin. Pycnogenol may stimulate the immune system. A high number signals high blood pressure. ", American Heart Association: Understanding Blood Pressure Readings., Iranian Journal of Public Health: "Effect of Pycnogenol Supplementation on Blood Pressure: A Systematic Review and Meta-analysis. This study adds to a body of research showing the benefits of Pycnogenol . This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [12, 13]. WebMD does not provide medical advice, diagnosis or treatment. However, this was a relatively small study, so larger ones are needed to fully understand pine bark extracts role in these findings. There are also several other natural ADHD remedies you can try. As I mentioned, pine bark extract is superior when it comes to antioxidants. Pycnogenol is not approved by the FDA for medical use. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. returned. Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. are clickable links to these studies. After taking a break for one to two weeks, they can start taking it again for several weeks. Some people who have asthma have higher levels of leukotrienes in their blood. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. For allergies: 50 milligrams twice daily. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. Taking pine bark extract also increases the blood . This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Circulation and Jet Lag on Long Flights. More research is needed to see how this supplement affects all of these conditions. No side effects were noted, unlike its synthetic counterpart. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. Plus, it reduced total and LDL (bad) cholesterol. This makes it very hard to set a standard dose. The studies revealed that the sperm concentration greatly increased after about eight to 16 weeks of treatment, to include improved orgasmic function. What Are These Tiny Red Spots on My Skin (Petechiae)? This condition is due to the pooling of blood in the veins of the lower legs. (14, 15). The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. 5) Inflammation and Allergies. Proper nutrition is essential for ADHD treatment. In a study of 72 children undergoing cancer chemotherapy, Pycnogenol reduced painful mouth ulcers, both alone and in combination with vitamin E [79]. The dosage in most clinical studies varied between 50-360 mg/day. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. Take Helpful Supplements. 7. Millions are hospitalized each year for . A trial of 86 people with eye damage from diabetes found that antioxidant therapy (including pycnogenol, vitamin E, and Coenzyme Q10) may improve eye health and reduce reactive oxygen species levels [35]. Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. Prenatal nutrition can be confusing. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. Various studies, referenced at uofmhealth.org, have shown that a daily dosage of Pycnogenol . All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. COPD. Chemistry. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Pycnogenol also potentially improved cognitive function in 78 people with mild cognitive impairment. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. Another highlight of grapes nutrition is the presence of polyphenols, which have been shown to decrease chronic inflammation.